Sutrisno, Rensa Dwi Assyfah, Rini Retnosari, Ihsan Budi Rachman, Husni Wahyu Wijaya
Enhancement of bacterial resistance has not been comparable by the development of new antibacterial, therefore the search for substances that have the potential as antibacterial needs to be developed. One of the substances that have antibacterial activity is fatty acids obtained through the hydrolysis of triglyceride acids (oils or fats). Triglyceride oils are contained in many plants, especially in their seeds. Candlenut seeds (Aleurites moluccana) contain triglycerides, reaching 55-66% of the weight of the seeds. This study aims to determine the antibacterial activity of candlenut oil derivatives, namely potassium soap, fatty acids, and their methyl esters. Stages of the research carried out include: (1) synthesis, characterization, and identification of potassium soap (2) synthesis, characterization, and identification of fatty acids, (3) synthesis, characterization, and identification of methyl esters, and (4) antibacterial activity test for potassium soap, fatty acids, and methyl esters against Staphylococcus aureus and Escherichia coli. The results showed that potassium soap, fatty acids, and methyl esters had antibacterial activity. Inhibition zone diameters produced by potassium soap, fatty acids, and methyl esters at a concentration of 1% against Staphylococcus aureus respectively 12.07, 8.75, and 6.67 mm and against Escherichia coli 12.18, 11.02, 7.32 mm, while at a concentration of 2% against Staphylococcus aureus respectively 13.20, 9.77, 7.33 mm and against Escherichia coli 14.00, 13.23 and 8.70 mm. © 2020 American Institute of Physics Inc.. All rights reserved.
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang No. 5, Malang, 65145, Indonesia
