I. Wayan Dasna, Dewi Mariyam, Husni Wahyu Wijaya, Ubed Sonai Fahruddin Arrozi, Sugiarto Sugiarto
Three zinc(II) complexes containing 4-aminopyridine (4-NH2 py) [Zn(4-NH2 py)2 (NCS)2] (1), [Zn(4-NH2 py)2 Cl2] (2), and [Zn(4-NH2 py)2 (NCS)Cl] (3) were synthesized and characterized by FTIR and single crystal X-ray diffraction. All complexes adopt a slightly distorted tetrahedral geometry with different crystal packing. Complex 1 crystallizes in the orthorhombic Pmmn space group, complex 2 in the monoclinic C2/c space group, and complex 3 in the orthorhombic Pbca space group. Non-covalent interactions such as NC-S···H,-Cl···H, and μ-μ stacking interaction between 4-NH2 py and other ligands (NCS− and Cl− ) are observed in the crystals packing. In vitro, antibacterial screening of all complexes was evaluated against two bacteria (Escherichia coli and Staphylococcus aureus). The results show that 1 has the highest antibacterial activity than 2 and 3. This difference is due to differences in the interactions elicited by the anion ligands. © 2023, Gadjah Mada University. All rights reserved.
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang No. 5, Malang, 65145, Indonesia; Center of Advanced Material for Renewable Energy, Universitas Negeri Malang, Jl. Semarang No. 5, Malang, 65145, Indonesia; Department of Applied Chemistry, Graduate School of Advanced Science and Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-Hiroshima, 7398527, Japan
