Muhammad Mahdum Rosyid, Nurul Elfiyah, Subandi Subandi, Evi Susanti, Sumari Sumari, Muntholib Muntholib
Obesity is a health problem whose prevalence increases along with the level of human welfare. Currently, obesity is prevented by inhibiting the activity of the pancreatic lipase enzyme involved in fat metabolism using orlistat. However, long-term use of orlistat can cause side effects. Watermelon mesocarp has inhibitory activity against pancreatic lipase enzyme which allows it to be used as an anti-obesity herb. However, its organoleptic properties are not favored by consumers. The aims of this research are to investigate (1) the effect of watermelon endocarp on the watermelon mesocarp inhibitory power in inhibiting pancreatic lipase and (2) the composition of the watermelon mesocarp-endocarp mixture whose organoleptic properties is acceptable. This research was carried out in three stages, (1) preparation of watermelon mesocarp and endocarp, (2) optimization of watermelon mesocarp-endocarp mixture as pancreatic lipase inhibitor, and (3) organoleptic test of watermelon mesocarp and endocarp mixture. The results showed that the endocarp increased mesocarp inhibitory power against pancreatic lipase with the optimum endocarp-mesocarp mass ratio of 2:1. The endocarp-mesocarp mass ratio of 2:1 also has the best organoleptic properties compared with the other compositions. The average scores for taste, aroma, and color were 5 (neutral), 7 (like), and 7 (like) respectively. © 2023 Author(s).
Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of Malang, Jl. Semarang No. 5, Malang, 65145, Indonesia; PT. Himikarta, Jl. Aris Munandar No. 53, Malang, 65119, Indonesia
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