Rini Retnosari, Nadia Erlina Mayangsari, Siti Marfu'Ah, Sutrisno Sutrisno, Ihsan Budi Rachman
The 9-(4-bromophenyl)-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione (Compound 1) was successfully synthesized using the green synthesis method. The purpose of the use of a green catalyst lemon juice and ultrasound-assisted method was to reduce temperature, time, and hazardous waste reaction. Uncatalyst reaction produced the yield of compound 1 47.31 % when water was used as the solvent. On the other hand, there was an increase in yield when lemon juice was used as an acidic catalyst, and the yield changed to 59.14%. Meanwhile, another product was formed in significant amounts when we used these methods. The product was 2-(4-bromo benzylidene) cyclohexane-1,3-dione (Compound 2). These reaction results will be discussed further in the talk. The antibacterial test shows that compound 1 has no antibacterial activity against Staphylococcus aureus and Escherichia coli. © 2023 Author(s).
Department of Chemistry, Faculty of Mathematics and Natural Sciences, State University of Malang, Malang, Indonesia