Abdul Hakim Md Yusop, Wan Fahmin Faiz Wan Ali, Farah Hidayah Jamaludin, Fatihhi Szali Januddi, Murni Nazira Sarian, Norazalina Saad, Tuck-Whye Wong, Arif Hidayat, Hadi Nur
The present study evaluates the corrosion behavior of poly[xylitol-(1,12-dodecanedioate)](PXDD)-HA coated porous iron (PXDD140/HA-Fe) and its cell-material interaction aimed for temporary bone scaffold applications. The physicochemical analyses show that the addition of 20 wt.% HA into the PXDD polymers leads to a higher crystallinity and lower surface roughness. The corrosion assessments of the PXDD140/HA-Fe evaluated by electrochemical methods and surface chemistry analysis indicate that HA decelerates Fe corrosion due to a lower hydrolysis rate following lower PXDD content and being more crystalline. The cell viability and cell death mode evaluations of the PXDD140/HA-Fe exhibit favorable biocompatibility as compared to bare Fe and PXDD-Fe scaffolds owing to HA's bioactive properties. Thus, the PXDD140/HA-Fe scaffolds possess the potential to be used as a biodegradable bone implant. © 2024 Wiley-VCH GmbH.
Materials Research & Consultancy Group (MRCG), Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Johor, Malaysia; Department of Materials, Manufacturing and Industrial Engineering, Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Johor, Malaysia; Advanced Membrane Technology Research Centre, Universiti Teknologi Malaysia, Johor, Malaysia; Advanced Facilities Engineering Technology Research Cluster (AFET), Plant Engineering Technology (PETech) Section, Malaysian Institute of Industrial Technology, Universiti Kuala Lumpur, Johor, Masai, Malaysia; Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, Selangor, Bandar Baru Bangi, Malaysia; Laboratory of UPM – MAKNA Cancer Research, Institute of Bioscience, Universiti Putra Malaysia, Selangor, Serdang, Malaysia; Department of Physics, Faculty of Mathematics and Natural Sciences Universitas Negeri Malang, Malang, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Malang, Indonesia; Center of Advanced Materials for Renewable Energy (CAMRY), Universiti Negeri Malang, Malang, Indonesia
