Galih Satrio Putra, Sumari Sumari, Melanny Ika Sulistyowaty, Magdalena Sri Handayani, Farida Suhud, Dini Kesuma, Farida Anwari
This research aims to analyze 500 samples for illicit drugs and NPS (New Psychoactive Substances) using GC-MS (Gas Chromatography Mass Spectrometry) in East Java Indonesia. Sample analysis was carried out by GC-MS with HP-5 column, injection port temperature of 250°C. Column temperature was maintained at 100°C for 2 minutes. It was then raised from10°C/minute to 280°C and maintained for 5 minutes Based on the results, it was detected 244 (48.8 %) Methamphetamine (MA); 30 (6 %) 3,4-Methylenedioxymethamphetamine (MDMA); 44 (8.8 %) 3,4-Methylenedioxyethylamphetamine (MDA); 56 (11.2 %) 3,4-Methylenedioxyethylamphetamine (MDEA); 106 (21.2 %) AB-Fubinaca; 5 (1.0 %) Tramadol; 5 (1.0 %) Ketamine; and 10 (2.0 %) Mephedrone. The identification of illicit drugs and NPS in confiscated materials was successfully achieved via GC-MS. The availability of GC-MS libraries is of great assistance in the identification of new drugs. Alternatively, the study of characteristic molecule fragments combined with the determination of their accurate masses can be a useful approach to identify unknown samples that were not previously analyzed. © 2024 Assiut University. All rights reserved.
Department of Chemistry, Faculty of Mathematics and Natural Sciences State University of Malang, Malang, 65145, Indonesia; Department of Pharmaceutical Sciences, Faculty of Pharmacy Universitas Airlangga, Surabaya, 60115, Indonesia; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Surabaya, 60293, Indonesia; Medical Laboratory Science, University of Anwar Medika, Sidoarjo, 61262, Indonesia
