S. Kharomah, M.J. Ramadhan, N.A. Zahrah, M. Agustin, D. Mirandah, A. Fauzi, S. Zubaidah
Acrylamide is a chemical compound that can be formed in some foods cooked at high temperatures. This chemical substance has the potential to cause various health problems, although some publications report findings to the contrary. The purpose of this study was to analyze the effect of acrylamide consumption and strain type on crawling performance in Drosophila melanogaster larvae: crawling speed and number of beats. This experimental study divided Drosophila into groups without consumption, consumption of 24 mg/kg bw/day and consumption of 48 mg/kg bw/day. In the crawling speed parameter, only the strain factor had a significant effect (F = 24.580, p < 0.001), while acrylamide consumption (F = 0.706, p = 0.519) and interaction factors did not have a significant effect (F = 0.782, p = 0.565). Strain also had a significant effect on the number of twitches (F = 4.555, p = 0.043), while acrylamide administration (F = 0.731, p = 0.508) and the interaction of the two factors (F = 0.426, p = 0.787) did not have a significant effect. The results of this study indicate that acrylamide does not have a significant effect on the crawling performance and number of beats of D. melanogaster larvae, although differences between strains have a significant impact. These findings have implications for assessing the risk of toxicity to human health. Genetic variation between individuals has the potential to influence individual sensitivity to acrylamide exposure. © Published under licence by IOP Publishing Ltd.
Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Indonesia; Department of Biology Education, Faculty of Teacher Training and Education, Universitas Muhammadiyah Malang, Indonesia
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