Nur Safinatun Najah, Latifatul Aisyah Nabila, Reni Rusidah, Siti Azimatul Luthfiyyah, Ahmad Taufiq, Nurul Hidayat
Diabetes Mellitus (DM) affects not only adults but also children, leading to an urgent need for the development of a reliable glucose sensors. This study introduces a simple method to develop a Localized Surface Plasmon Resonance (LSPR)-based glucose sensor utilizing silver nanoparticles (AgNPs). AgNPs were synthesized using pulsed Nd:YAG laser ablation in liquid at different laser-pulse diameters ranging from 1 mm to 5 mm. The wavelength, energy, and frequency of the Nd:YAG laser were fixed at 1064 nm, 200 mJ, and 4 Hz, respectively. The morphology of AgNPs was observed to be spherical, with an average diameter of 42.5 nm. Analysis of the UV-Vis results showed that the interaction of AgNPs with glucose at various concentrations (i.e., 0–10%), resulted in changes in the LSPR wavelength. The wavelength shifted to longer values as the glucose concentration increased. The AgNPs’ sensing sensitivity to detect glucose was 0.421 nm/%, with excellent linearity (0.98) and a detection range from 0% to 10%. These findings provide significant contributions to the development of reliable glucose sensors, with important application prospects in the management of diabetes mellitus. © (2025), (Suranaree University of Technology). All rights reserved.
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang 5, Malang, 65145, Indonesia; Center for Instrumentation and Sensing Technology, Universitas Negeri Malang, Jl. Semarang 5, Malang, 65145, Indonesia
