Sri Ainaiyah Ariadi Putri, Sunaryono Sunaryono, Nadiya Miftachul Chusna, Nasikhuddin Nasikhuddin, Kormil Saputra
In this research, the synthesis of Fe3O4/Ginger Extract nanomaterials has been successfully used the coprecipitation method. The SNEDDS consists of virgin coconut oil (VCO), tween 80 as a surfactant, and PEG as a cosurfactant. The results of characterization using FTIR showed that the functional groups of SNEDDS-Fe3O4/ginger extract ferrofluids were formed. The characterization sample was carried out using the FTIR, XRD, PSA instrument, and antioxidant activity. The results of the characterization using FTIR instrument showed that vibration of C=C aromatic (flavonoids) at 1533-1502 cm-1. Its bond is indicating the presence of zingiber officinale extract. While Fe-O at 503-435 cm-1. The XRD instrument shows the X-ray diffraction pattern of the Fe3O4/ginger extract crystal phase with a crystal size of about 13.2 nm. This result was confirmed with characterization using the PSA instrument. PSA instrument resulted in the particle size distribution of SNEDDS-Fe3O4/ginger extract ferrofluids around 14.72 nm. Antioxidant activity characterization of the SNEEDS shows that the sample has excellent antioxidant activity with a percentage of antioxidants of about 22.1 μg/mL. The SNEDDS-Fe3O4/Ginger Extract which resulting was an excellent drug emulsifier with targeted drug applications. © 2025 American Institute of Physics Inc.. All rights reserved.
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang No. 5, Malang, 65145, Indonesia; PUI-PT Centre of Advanced Materials for Renewable Energy, Universitas Negeri Malang, Jalan Semarang No. 5, Malang, 65145, Indonesia; Department of Chemistry Education, Faculty of Learning and Science Education, Institute of Studi Islam Sunan Doe, Jl. Soekarno Hatta, Lombok Timur, 83671, Indonesia
