Abdul Gofur, Sri Rahayu Lestari
Objective To analyze the effect of black soybean natto treatment on the recovery of the reproduction system in hypercholesterolemic male mice model. Methods Thirty male mice were divided into five groups, they were normal mice (K−), a hypercholesterolemic mice model (K+), a hypercholesterolemic mice model with 200 mg/kg BW of natto extract (P1), a hypercholesterolemic mice model treated with 400 mg/kg BB of natto extract (P2), and a hypercholesterolemic mice model treated with 800 mg/kg BB of natto extract (P3). Natto extract was given orally for 30 d. Results Black soybean natto extract influenced on reproduction system of male hypercholesterolemic mice by increasing the testosterone level and increasing the density and motility of sperm. Conclusion Black soybean natto extract is promising as hypercholesterolemic therapy for treating the male reproduction system. © 2016 Hainan Medical College
Department of Biology, Faculty of Mathematic and Natural Sciences, State University of Malang, Malang, 65145, Indonesia
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